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KMID : 1007520030120020180
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Food Science and Biotechnology
2003 Volume.12 No. 2 p.180 ~ p.182
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Inhibitory Effects of Naturally Occurring Flavonoids on a Human Intestinal Bacterium, Clostridium perfringens
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Son, Dong-Ju
Lee, Sung-Eun/Park, Byeoung-Soo
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Abstract
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The growth-inhibiting activities of 16 naturally occurring flavonoids towards 5 human intestinal bacteria were examined using an impregnated paper disk method and compared with those of tetracycline and chloramphenicol. Four flavones, fisetin, morin, quercetin, and rhamnetin, inhibited the growth of Clostridium perfringens ATCC 13124. Fisetin and quercetin also inhibited the growth of Bifidobacterium bifidum ATCC 29521, whereas no inhibitory effect on the growth of B. bifidum was found in morin and rhamnetin. Except for scopoletin, all natural compounds showed no growth-inhibiting effects on Bacteroides fragilis, Lactobacillus acidophilus JCM 1028, and B. longum ATCC 15707. Scopoletin had weak inhibitory effects on the growths of B. fragilis and C. perfringens.
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